#663003 - 03/06/08 01:05 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info?
[Re: faeriewitch]
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Presto77
Enthusiast
Registered: 03/02/07
Posts: 288
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GHB is an amazing substance which used to be sold in health food stores, but succumbed to DEA Scheduling following widespread abuse. There's a great book on GHB (if you can find it) called, "GHB: The Natural Mood Enhancer - The Truth About GHB". Check out this site:
http://www.life-enhancement.com/article_template.asp?ID=76
Edited by Presto77 (03/06/08 01:08 PM)
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#663014 - 03/06/08 01:28 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info?
[Re: Presto77]
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faeriewitch
Veteran
Registered: 09/01/06
Posts: 519
Loc: Here
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Thank you for the article - I didn't know it could be used as an antidepressant, most of the literature says it can cause suicidal thoughts! Don't need that!
Because of all the abuse warnings in the product literature, I also checked out the Erowid vaults on GHB really just to see what dosages people were taking who had bad effects from it - and it really showed me what NOT to do - i.e. alcohol with it - I don't drink anyway so no problem there. (Erowid's a great place to learn how to avoid being stupid - heck people on there have smoked Dragon's Blood incense thinking it was some kind of "Red Rock Opium" - but I digress...)
I have learned my lesson from bad experience with dangerous meds when I had a seizure from Tramadol (Click here for TramadolX180tabs for only 99.95 dollars) so I am looking for warnings of people who may have had or heard of adverse effects from therapeutic dosages of this stuff.
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#663029 - 03/06/08 01:41 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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nephro
GRAND Pooh-Bah
Registered: 09/04/06
Posts: 8817
Loc: UK, despite the rumours
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I don't think you have any more to worry about than with most other drugs that are new to you. However, the BNF states that benzodiazepines and opioids should be AVOIDED (red warning). Tricyclics and antipsychotics may interact, but they are not absolutely contra-indicated with sodium oxybate.
The warnings about benzodiazepines and opioids are particularly important as the drug can cause anxiety, joint pain and abdominal pain.
Here is the full list of side-effects, but remember they include every possibility these days:
nausea, vomiting, diarrhoea, abdominal pain, anorexia; hypertension, peripheral oedema; dyspnoea; sleep disorders, confusion, disorientation, impaired attention, depression, drowsiness, anxiety, dizziness, headache, tremor, asthenia, fatigue; urinary incontinence, nocturnal enuresis; arthralgia, muscle cramps; blurred vision; sweating; less commonly faecal incontinence, myoclonus, psychosis, paranoia, hallucination, agitation, amnesia, and rash; rarely dependence; respiratory depression, seizures, and urticaria also reported
I am assuming you will be starting off on a low dose and titrating upwards; this usually minimises side-effects.
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#663033 - 03/06/08 01:45 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: nephro]
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faeriewitch
Veteran
Registered: 09/01/06
Posts: 519
Loc: Here
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Thanks Nephro. I should be clear then because I will be taking this INSTEAD of benzos, and I'm no longer taking any opiates, plus I avoid tricyclics like the plague since that in combo with the Tramadol (Click here for TramadolX180tabs for only 99.95 dollars) gave me the seizure...
It appears that the side effects only occur if you don't go to bed immediately after taking it - I hope to keep the dose as low as possible to avoid side effects - the info sites also state "serious withdrawal" but the more I read the less stock I put in that one. The "bedwetting" is the one that particularly worries me. Who the heck wants that? I've never been prone to it though. What do you think?
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#663037 - 03/06/08 01:48 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info?
[Re: faeriewitch]
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Presto77
Enthusiast
Registered: 03/02/07
Posts: 288
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I have learned my lesson from bad experience with dangerous meds when I had a seizure from Tramadol so I am looking for warnings of people who may have had or heard of adverse effects from therapeutic dosages of this stuff. I took GHB for years, and the worst adverse effect I ever had was nodding out at work (and I shouldn't have taken it at work!). At theraputic doses (and that is the key), there were NO adverse effects.
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#663046 - 03/06/08 02:03 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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nephro
GRAND Pooh-Bah
Registered: 09/04/06
Posts: 8817
Loc: UK, despite the rumours
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You probably wouldn't have seized on Tramadol (Click here for TramadolX180tabs for only 99.95 dollars) if TCAs weren't involved.
It sounds like sodium oxybate may have some effect on certain smooth muscles, but if you aren't sleeping well anyway I'm sure you'll be alerted to any desire to pass urine. I still think nothing to worry about, as long as you start on low doses and wait a while before gradually increasing if needed.
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#663051 - 03/06/08 02:11 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: nephro]
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faeriewitch
Veteran
Registered: 09/01/06
Posts: 519
Loc: Here
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Thanks again Nephro. Yes you're certainly right about the Tramadol (Click here for TramadolX180tabs for only 99.95 dollars)/tri combo. The doc who gave me the Ultram KNEW I was on Doxepin so that was her bad, IMHO.
The dosage will definitely be titrated up from I believe 2.5 ml up to 9 if necessary (split dosages). I'm hoping not to have to go above 6 because it seems that's when the side effects start to kick in. Oh well if this doesn't work there's always, um, chloral hydrate maybe?
A frying pan over the head would be a good one but that might cause quite a hangover. Seriously tho, thanks for the encouragement. I was afraid I was going to hear "DON'T DO IT" about this stuff.
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#663414 - 03/07/08 06:06 AM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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Presto77
Enthusiast
Registered: 03/02/07
Posts: 288
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It's the only substance that is assigned Sched I and Sched III simultaneously.
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#663518 - 03/07/08 09:10 AM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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NotBillGates
GRAND Pooh-Bah
Registered: 01/15/04
Posts: 2873
Loc: 867-5309
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EXCELLENT - I just got a call from the central pharmacy about my Rx and my insurance approved it for me with a copay of $45.00 - quite affordable.
That's great news FaerieWitch. Please keep us updated as how it helps you with your sleep.
-=NBG=-
_________________________
“Choosing Obama is a great opportunity for Americans to show the world they can change, be humble and learn from their mistakes." - Nelson Mandela
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#665945 - 03/11/08 06:59 AM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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superscapes
GRAND Pooh-Bah
Registered: 05/14/06
Posts: 3825
Loc: ohio
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Looks like it's going to take about a week or more for this whole paper process before they can even send the bottle to me - I expect to have it by the end of month. Do you want to hear the step by step process as I go through it? I'll be clean, depending upon what they look at. I think really they wanna make sure you're not susceptible to diversion which I'm too old for that kinda [censored] anymore.
I know I would be interested in hearing your experience. Insomnia absolutely sucks, and it sounds like you have a BAD case. Best of luck to you FW!
Oh...I forgot to add..you aren't the only one who has to deal with that "paperwork process". My pain mgmt doc made me contact an ex-FBI agent who now does background checks, and get mine checked for diversion purposes. That was $200 wasted. I haven't even had a speeding ticket!
_________________________
McCain/Palin in '09!
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#666998 - 03/12/08 05:12 PM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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superscapes
GRAND Pooh-Bah
Registered: 05/14/06
Posts: 3825
Loc: ohio
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They made YOU pay for the background check? That blows Aardvark wind! (a cute way of saying "that sucks")
Yep. They made me pay for it. The retired agent then sent my pain doc a certficate saying this "An extensive background investigation has been conducted concerning Mr. Smith. The investigation revealed nothing negative concerning Mr. Smith, nor did it reveal anything that may concern a physician who would prescribe any type of medicine for Mr. Smith."
Anywho...Keep us posted on how the Xyrem works. I bet you are due for a good nights sleep!
_________________________
McCain/Palin in '09!
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#667814 - 03/14/08 08:35 AM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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Presto77
Enthusiast
Registered: 03/02/07
Posts: 288
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Allow me to share my experience after using GHB for about 3 years... GHB induced a very deep, restful (stage 4) sleep, but metabolized off after about 2-3 hours - at which time I would wake up (usually full of energy). I always needed the second dose to get back to sleep. As a matter of fact, I began to miss getting a full night's uninterrupted sleep!
I think you'll quickly discover that you don't need an alarm clock for the second does. Instead, you will invariably wake up after a couple of hours. Please let us know how it works out for you. I predict you're going to be completely amazed at how well you sleep, and how good you're going to feel!
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#668339 - 03/15/08 07:48 AM
Re: Prescribed Xyrem for sleep (i.e. GHB) - anyone have info
[Re: faeriewitch]
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faeriewitch
Veteran
Registered: 09/01/06
Posts: 519
Loc: Here
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Well, day one, no go. It made me seriously dizzy after about 20 minutes but when I laid down I did not fall asleep, and even 3 hours later when I took the 2nd dose I did not sleep. So I'll give it the rest of the weekend at this dose then call the doc Monday if it doesn't start working and see what we do next, since this was just the starting dose of 2.25g (x2).
With how dizzy it made me I'm surprised it did not work, because that's usually the kickstart that makes me able to sleep (for one or two or hours) from Ambien or Soma/carisoprodol.
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